The Aesthetic Wonders of Polynucleotide Therapy


'After just three sessions of polynucleotide injections under my eyes, I saw a significant reduction in dark circles and fine lines. My skin feels more hydrated and firmer.'

What are Polynucleotides and How Do They Work?


The building blocks of DNA are polynucleotides, and these molecules that make up our genetic information can be used to improve the skin’s appearance. Polynucleotides are widely used in medicine and science, including gene therapy and vaccines, but as we understand more about these molecules, we are discovering new and exciting uses for them in the area of aesthetics. DNA from the sperm of fishes such as salmon and trout are the source of polynucleotides for the cosmetic industry and, in particular, at The Real Clinic. Once they are purified and sterilised, they are very well matched to the human skin and produce positive biological results. If you are interested in learning more about the science of polynucleotides, please click here.


In the body, polynucleotides help the repair of damaged skin cells and support the skin’s natural healing processes. They cause these effects by providing the skin with extra nucleotides to promote the renewal of skin cells, activating fibroblasts and making collagen, both of which form the scaffolding of the skin, and by decreasing inflammation and angiogenesis, the process of creating new blood vessels within the skin. This is essential for the process of healing and delivering nutrient-rich blood to skin.


There are many cosmetic indications of polynucleotides. Polynucleotides are injected and can be used all over the body for different purposes, but the most common treatment areas are under the eyes and in the middle of the face. When they are injected here, the extra collagen and cellular regeneration leads to increased hydration and skin elasticity. This helps to treat fine lines and wrinkles, reducing the appearance of darkness and redness. Polynucleotides are also used to increase hair growth by stimulating the regeneration of hair follicles. They are particularly effective for androgenic alopecia, that is hair loss caused by steroid hormone use. Polynucleotides have further been a widespread treatment for scars, including acne scarring, by promoting wound healing.


Safety and Efficacy


Polynucleotide treatments are becoming increasingly used in aesthetics and at The Real Clinic, mainly due to their effectiveness, safety and versatility as well as simple manner in which the treatment is provided. They are particularly effective when combined with other treatments such as microneedling and, in reflection of this, have been recommended by lots of skin and aesthetic doctors around the world. More research into their uses will see their popularity continue to grow. Demand for treatment is progressively increasing as patients experience meaningful benefits to their skin health and spread the word.


Patient Testimonials


Patients who have had polynucleotide treatments notice improvements in their skin texture and overall appearance. One of our patients shared her experience: 'After just three sessions of polynucleotide injections under my eyes, I saw a significant reduction in dark circles and fine lines. My skin feels more hydrated and firmer.'


Scientific Evidence and Research


Lots of studies have been carried out showing that these treatments work. In fact, research published in the Journal of Cosmetic Dermatology indicates that polynucleotides significantly improve skin hydration, elasticity and overall appearance. Moreover, another study in the Aesthetic Surgery Journal showed that combining polynucleotide injections with other treatments like microneedling enhances the overall results, resulting in a more radiant and youthful appearance of the skin.


Future Trends and Developments


Looking ahead, the future of polynucleotide treatments in aesthetics is bright and incredibly promising. With more research and development, new applications and improved formulations are on the horizon. The future may include topical polynucleotide treatments, combination therapies with other skin treatments, and more advanced delivery systems to help them work even better than they already do.


Conclusion: Here to Stay


Polynucleotide treatments are here to stay. Their increasing popularity among both patients and clinicians will ensure their position at the forefront of aesthetics at The Real Clinic. As more people seek non-surgical and effective solutions for skin repair, polynucleotides are an excellent option backed by science and patient satisfaction.


Dr Tony Fordham – Aesthetics Doctor and Trainer


To learn more about Tony, just click here. To book at appointment, please click here info@realclinic.uk


RETURN TO BLOG
By Jonathan Hewiit June 3, 2025
Mounjaro
By Neel Desai November 15, 2024
'In this blog, The REAL Clinic addresses common questions about abdominoplasty, covering everything from types of tummy tuck to recovery.'
By Annakan Navaratnam November 4, 2024
'Rhinoplasty has been traditionally been considered an elective procedure for younger patients. However, increasingly older patients are undergoing nasal surgery for both functional and aesthetic indications.'
By The REAL Clinic October 22, 2024
'In this blog, the REAL Clinic addresses common questions about breast augmentation, covering everything from implant types and surgical details to recovery.'
By Konal Saha October 8, 2024
'One of the most common concerns I hear from patients is about hooded upper eyelids, giving them an aged and tired appearance that is completely at odds with how they feel. The great news is that a blepharoplasty procedure on the eyelids can be hugely helpful at a relatively low cost and short recovery time.'
By Laura Summers September 27, 2024
“Help! My belly button has swallowed my dressing!” (Disclaimer, patient and belly button were fine!)  This is just one of the thousands of messages that are received from patients to our holistic and virtual nursing postoperative support service which is provided for Mr Naveen Cavale’s patients who have undergone cosmetic and plastic surgery at The REAL Clinic
By Neel Desai September 9, 2024
'At The REAL Clinic, your comfort, safety and individual needs are at the core of everything we do.'
July 10, 2024
Perimenopause and menopause bring numerous changes to a woman’s body, often impacting gut health. Many find themselves facing sudden weight gain, food intolerances, and uncomfortable symptoms like bloating, gas, and reflux. However, there’s good news! As we gain more insights into gut health, we discover powerful tools and practices that can support our well-being during this time.
June 13, 2024
Renowned plastic surgeon Mr Naveen Cavale, founder of The REAL Clinic, has recently launched an exciting new podcast series, the REAL Clinic Podcast , sponsored by 42 South Films .
April 17, 2024
Not everyone wants to undergo the knife which leads many individuals to seek non-surgical options to rejuvenate their facial appearance. Here are The REAL Clinic, we offer a range of cutting-edge treatments designed to enhance your natural beauty. Below, we explore the key non-surgical options that are greatly popular amongst our patients.
More Posts